
Prof. Dr hab. Barbara Czochralska
Division of Biophysics
Institute of Experimental Physics
University of Warsaw
Phone:
E-mail: barc@biogeo.uw.edu.pl
Research interests
- Electrochemistry and photochemistryof biologically active compounds: nucleic bases and coenzymes.
- Molecular photophysics: laser flash photolysis of coenzymes,and nucleosides of chemotherapeutic significance.(antivirus and antileucamic drugs).
Methods
- Electrochemistry
- Photochemistry
- Fluorescence
- Laser flash photolysis
Professional experience
1962 | Ph.D. Jagiellonian University (Cracow) |
1963 - 1974 | Assist. Professor, University of Warsaw |
1973 - 1974 | Post-doctoral stay, Department of Chemistry, University of Michigan, Ann Arbor, USA (Fulbright Fellowship) |
1975 | and Johns, Hopkins University, Baltimore,USA |
1975 | Habilitation (Assoc. professor), University of Warsaw |
1977, 1979, 1982, 1983 | 3 - months stays in the Institue of Physical Chemistry, KFA, Julich, Germany |
1983 - 2000 | several stays as visiting professor in the Institute of Molecular Photophysics, Univerite Paris-Sud, CNRS, Orsay, France (Research cooperation) |
Selected publications
- B.Czochralska, D.Shugar, S.Arora, R.Bates and R.S.Cutler, Structure,cyclization and other properties of the electrochemical reduction product of 4,6-dimethylpyrimidon-2,: J.Am.Chem.Soc. 99 (1977) 2583.
- Badanie mechanizmów elektroredukcji pochodnych zasad nukleinowych (The electroreduction mechanisms of nucleic bases derivatives.) Wydawnictwo Uniwersytetu Warszawskiego. Warszawa 1977
- B.Czochralska and L.Lindqvist, Biphotonicoxidation of NADH on laser excitation 353nm, Chem. Phys. Letters 101(1983) 297
- B.Czochralska, M.Wrona and D.Shugar, Electrochemically induced, photochemically reversible dimers of pyrimidine and purine, Springer Verlag: Topics in Current Chemistry, 30 (1986) 133-181
- B.Czochralska,B.Bojarska, K.Pawlicki and D.Shugar, Photochemical and enzymatic redox transformations of reduced forms of coenzyme NADP+, Photochem. Photobiol. 51(1990) 401
- L.Lindqvist, B.Czochralska and W.Kawczyński, Intermediates in the oxidation of a dihydrpyridine derivative of AZT related to AIDS dementia, studied by nanosecond laser photolysis, J.Photochem.Photobiol. B.Biol. 23 (1994) 207-211.
- Wrażliwość materii (Sensibility of matter) Wydawnictwo DIG, Warszwa 1998.
- B.Czochralska and L.Lindqvist, Reaction mechanism in the photochemistry of the antileuceamic agents 2-chloro and 2-bromo-2'deoxy adenosine, studied by nanosecond laser flash photolysis, J.Photochem. Photobiol. B.Biol. (1999)28-32).
- L.Lindqvist, B.Czochralska, M.-P.Fontaine-Aupart, W.Kawczyński, F.Tfibel and T.Douki, Photochemistry of 2-chloropyrimidine, Photochem.Photobiol.Sci.,1 (2002)600-606.