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Name: Prof. Dr. hab. Barbara Czochralska
Address: Department of Biophysics,
Institute of Experimental Physics, Warsaw University,
Zwirki i Wigury 93, 02-089 Warsaw, Poland
Phone: +48 22 5540779
E-mail: barc@biogeo.uw.edu.pl
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Research interests:
- Electrochemistry and photochemistryof biologically active compounds: nucleic bases and coenzymes.
- Molecular photophysics: laser flash photolysis of coenzymes,and nucleosides of chemotherapeutic significance.(antivirus and antileucamic drugs).
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Methods:
- Electrochemistry
- Photochemistry
- Fluorescence
- Laser flash photolysis
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Professional experience:
| 1962 |
Ph.D. Jagiellonian University (Cracow) |
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| 1963 - 1974 |
Assist. Professor, University of Warsaw |
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| 1973 - 1974 |
Post-doctoral stay, Department of Chemistry, University of Michigan, Ann Arbor, USA
(Fulbright Fellowship) |
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| 1975 |
and Johns, Hopkins University, Baltimore,USA |
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| 1975 |
Habilitation (Assoc. professor), University of Warsaw |
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| 1977, 1979, 1982, 1983 |
3 - months stays in the Institue of Physical Chemistry, KFA, Julich, Germany |
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| 1983 - 2000 |
several stays as visiting professor in the Institute of Molecular Photophysics,
Univerite Paris-Sud, CNRS, Orsay, France (Research cooperation) |
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Selected publications:
- B.Czochralska, D.Shugar, S.Arora, R.Bates and R.S.Cutler,
Structure,cyclization and other properties of the electrochemical reduction product
of 4,6-dimethylpyrimidon-2,: J.Am.Chem.Soc. 99 (1977) 2583.
- Badanie mechanizmów elektroredukcji pochodnych zasad nukleinowych
(The electroreduction mechanisms of nucleic bases derivatives.)
Wydawnictwo Uniwersytetu Warszawskiego. Warszawa 1977
- B.Czochralska and L.Lindqvist,
Biphotonicoxidation of NADH on laser excitation 353nm,
Chem. Phys. Letters 101(1983) 297
- B.Czochralska, M.Wrona and D.Shugar,
Electrochemically induced, photochemically reversible dimers of pyrimidine and purine,
Springer Verlag: Topics in Current Chemistry, 30 (1986) 133-181
- B.Czochralska,B.Bojarska, K.Pawlicki and D.Shugar,
Photochemical and enzymatic redox transformations of reduced forms of coenzyme
NADP+, Photochem. Photobiol. 51(1990) 401
- L.Lindqvist, B.Czochralska and W.Kawczyński,
Intermediates in the oxidation of a dihydrpyridine derivative of AZT related to AIDS
dementia, studied by nanosecond laser photolysis,
J.Photochem.Photobiol. B.Biol. 23 (1994) 207-211.
- Wrażliwość materii (Sensibility of matter)
Wydawnictwo DIG, Warszwa 1998.
- B.Czochralska and L.Lindqvist,
Reaction mechanism in the photochemistry of the antileuceamic agents 2-chloro
and 2-bromo-2'deoxy adenosine, studied by nanosecond laser flash photolysis,
J.Photochem. Photobiol. B.Biol. (1999)28-32).
- L.Lindqvist, B.Czochralska, M.-P.Fontaine-Aupart, W.Kawczyński,
F.Tfibel and T.Douki,
Photochemistry of 2-chloropyrimidine,
Photochem.Photobiol.Sci.,1 (2002)600-606.
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Research
